Clinical System One (CS1-4B): 4B-parameter decision model for clinical records (arXiv:2610.27099v1)
Researchers introduce Clinical System One (CS1-4B), a 4-billion-parameter decision model trained on 12.4 million Q&A pairs from 3.6 million patients across a multi-hospital system that produces typed judgments and probabilities from full clinical records in a single forward pass. CS1-4B outperformed larger open decision models on most held-out tasks, achieved comparable aggregate performance to a tested 27B model with 6.4× faster inference, and when paired with a language-model agent enabled cited answers over multi-year histories and much more efficient trial-eligibility screening than keywords or full-record LLM reads.