AI model IRIS decodes signaling-pathway 'fingerprints' in embryonic cells
MIT and Whitehead researchers developed IRIS, a neural‑network model that detects pathway‑specific gene‑expression 'fingerprints' to infer which signaling pathways cells experienced; trained on large human embryonic stem‑cell datasets and validated on single cells from mouse gastrulation, the open‑access study was published in Nature Methods on Sept. 8.